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What Sintra Synergies Taught Me About Trust and AI
By Matt Wilkinson
There's a moment, somewhere between the second coffee and the fourth honest conversation of the day, when you realise the event you're attending is something different.
That's what happened in Sintra.
I was fortunate enough to join Joeri Billast and Mark Schaefer for the Sintra Synergies marketing retreat - a gathering of marketing leaders from across the world, set in one of Portugal's most extraordinary landscapes. Sintra sits in its own microclimate, a UNESCO-listed hill town where Moorish castles and Romanticist palaces emerge from the forest like something from a fever dream. The views out across the hillside were a constant reminder that some things still deserve your full, undivided attention.
So did the conversations.
Ideas are sharpened
A “fireside chat” between Joeri, Mark and the room brought together a genuinely diverse mix of marketing practitioners and leaders, all grappling with the same underlying tension: how do you stay human in a world where AI is becoming the default?
What struck me most wasn't the individual ideas, but the quality of the synthesis. When you put sharp people in a room with a shared vocabulary and no agenda to perform, thinking accelerates. The group moved quickly from:
"AI is changing everything"
to the harder, more useful questions:
“Where does AI augment and where must humans remain primary?”
“What does trust actually mean when your customer doesn't know whether they're talking to a bot or a person?”
“How do you build a brand that an AI engine will cite, recommend, and return to?”
These aren't abstract questions. They're the commercial questions that will define which life science companies grow through this period and which get left behind.
The ideas worth packing an extra suitcase for
A few things landed hard enough to stick.
The first: cognitive surrender is a real risk. As AI takes on more of the decision-making load, buyers may simply stop interrogating the recommendation. That makes brand equity and word-of-mouth not softer, more optional assets - but harder, more structural ones. The trusted brand becomes the override signal.
The second: transparency about AI is non-negotiable. Not because buyers are hostile to AI, but because discovering you've been deceived is catastrophic. The question isn't whether to use AI - it's whether you're honest about how.
The third, and most uncomfortable: the "human touch" is becoming a luxury differentiator. The most distinctive companies will be those that deliberately choose where to be slow, personal, and present. That's a strategic decision, not a resourcing constraint.
The thing conferences can't fake
I've been in enough webinars and virtual summits to know what gets lost in translation. The half-formed idea you share over lunch. The conversation that runs 20 minutes past the scheduled break because the room doesn't want to stop. The moment someone says something that reframes a problem you've been carrying for months.
Sintra Synergies had all of that.
Joeri - whose thinking on the future of CMO leadership we explored in a recent episode of A Splice of Life Science Marketing - created a space that felt genuinely generative. And Mark Schaefer, whose Uprising event I'd encourage anyone in marketing to put in their calendar, brought the kind of intellectual rigour and warmth that makes an event feel worth the flight.
I left with a notebook full of half-finished thoughts and a clearer sense of what the next 18 months demand from marketing leaders: more clarity about what AI is actually for - and the courage to protect the human parts that matter most.
Most importantly I left with a new group of friends who I look forward to collaborating with in the future.